Granulomatous lesions in fish: a histoplasma-like case
The examined fish showed no visible signs of disease during life. Mortality occurred predominantly at night. Gills were pale, and the fish were slightly emaciated. Necropsy revealed granulomas in the spleen and/or kidneys. Parenchymal organs were enlarged and anemic. The gross appearance was consistent with mycobacteriosis. However, Ziehl–Neelsen staining of impression smears from spleen and kidney did not reveal acid-fast bacteria. The granulomas were necrotic, a feature commonly associated with mycobacterial infections. ...
